Science

The Endocannabinoid System

The Endocannabinoid System was first discovered in 1992 as the mechanism through which THC, CBD, and all cannabinoids are absorbed into the body. This launched decades of scientific research and clinical studies into the therapeutic uses of the cannabis plant. 

The ECS is a regulatory system consisting of cannabinoid receptors, mainly CB1 and CB2. Cannabinoids help naturally restore balance to your body’s ECS. 

CB1 Receptors are present in the central nervous system, our brain, connective tissues, glands, gonads, organs, and spinal cord. They help provide powerful pain relief, regulate appetite and nausea, and include calming and euphoric effect in the brain. 

CB2 Receptors are mainly found in the immune system, gastrointestinal system, spleen, tonsils, thymus gland, bon marrow, and the reproductive organs. CB2 receptors are involved in the regulation of all our immune responses and modulate the intestinal inflammatory response.

Cannabis for Wellness

Sleep

During a good night’s sleep, the body works hard to repair damage and fight inflammation. 7-9 hours each night has been shown to improve memory, mood, and immune function. Conversely, lack of sleep can cause headaches, disease, brain lapses, and mood swings. Cannabis is a well-known sedative that encourages deep sleep by calming overactive thoughts and nervous systems. Try an indica-dominant strain 30 minutes before bed.

Mobility

The average American spends ~55% of their day sitting down and over time this can cause stiff joints and chronic pain. Lack of moment also prevents the endorphin boosting, cardiovascular, and fat burning benefits that exercise provides. Cannabis can effectively ease the aches and pains that prevent many from engaging in exercise. THC helps block pain signals while CBD’s anti-inflammatory power can soothe stiff joints and muscles. 30 minutes prior to workout apply topical CBD to swollen joints or hurting areas. Try an energizing sativa strain via vape or tincture. Post-workout apply a second topical layer of CBD to soothe soreness.

Calm

Regardless of the source, stress manifests through tensed muscles, rapid heartbeats, and digestive irregularities. Over the long term, such chronic suffering can also prevent the ECS from doing its job to regulate the body. A 2018 study at Washington State University found that two puffs of cannabis can help reduce bouts of anxiety. Consider micro-dosing throughout the day for lasting effects . For a more long-term zen, we recommend combining cannabis with a daily calming practice such as yoga or meditation.

Romance

Studies show that regular romance can promote better sleep, reduce stress and improve mood by pumping the body with more happy-hormones and pleasure-producing chemicals. Cannabis can relax the body, soothe soreness, and allow the brain to tune into the present moment.  Indica-dominant strains are preferred for a more relaxed experience, while sativas are best for a more energetic experience.

Optimized Formula-Entourage Effect

Optimized Formula – Designer Cannabis

For centuries humans have been consuming cannabis for mental health. Our full spectrum formula consists ONLY of natural plant cannabinoids and terpenes.

Why THC?

THC is only one of 85+ cannabinoids found in cannabis and is the primary psychoactive ingredient – it takes almost all the credit for creating your cerebral high.

Why also CBD?

CBD is the main non-psychoactive cannabinoid in the cannabis plant. CBD with THC helps minimize the possible side effects that come with getting too high such as paranoia, anxiety, and racing heart – helping you comfortably medicate.

Evidence?

The pharmaceutical drug Marinol, a synthetic form of THC available since the 1980s, showed to be a good appetite stimulant and also good at getting patients high and paranoid. When you just stimulate the CB1 receptor with this pure molecule, it’s intoxicating and patients don’t tolerate it very well. Another pharmaceutical drug Sativex – which combines THC and CBD – is tolerated much better.

Evidence contributed by Adie Wilson-Poe Ph.D., cannabis researcher at Legacy Research Institute.

Here are links to the clinical trials

Why Terpenes?

In creating our end product we use distillation to separate cannabinoids from terpenes and less desirable residuals such as chlorophyll and lipids. We add back terpenes for the flavor profile, about 3% of the total formula. Terpenes are found across the plant kingdom and are what gives plants their characteristic smell.

Entourage Effect

Also known as whole plant medicine, the notion is that all of the compounds in cannabis – including cannabinoids and terpenes – work most effectively and produce maximal therapeutic benefits when consumed together, rather than as isolated extracts. For more info about the entourage effect and cannabis science read this story on Wired

Our Process

FlowPen

Vape Cartridges

Our Process

FlowPen

Vape Cartridges